Phorbol Esters Enhance Exocytosis from Chromaffin Cells by Two Mechanisms
نویسندگان
چکیده
منابع مشابه
Phorbol esters enhance exocytosis from chromaffin cells by two mechanisms.
Treatment with phorbol esters such as 12-O-tetradecanoylphorbol acetate (TPA) rapidly enhances [3H]norepinephrine secretion from digitonin-permeabilized adrenal chromaffin cells. When TPA treatment was prolonged for several hours, a second distinct enhancing effect was observed. This later enhancement was most prominent at intracellular Ca2+ concentrations of 3-30 microM, and did not require th...
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ژورنال
عنوان ژورنال: Journal of Neurochemistry
سال: 1990
ISSN: 0022-3042,1471-4159
DOI: 10.1111/j.1471-4159.1990.tb13302.x